Glucocorticoids Regulate Circadian Rhythm of Innate and Adaptive Immunity
Animals have evolved circadian rhythms to adapt to the 24-h day-night cycle.Circadian rhythms are controlled by molecular clocks in the brain and periphery, which is driven by clock genes.The circadian rhythm is propagated from the brain to the periphery by nerves and hormones.Glucocorticoids (GCs) are a class of steroid hormones produced by the ad